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التصنيف: psoriasis
المادة الفعالة: acitretin

The major metabolite of etretinate with the advantage of a much shorter half-life when compared with etretinate.
Acitretin is an oral retinoid derived from vitamin A used mainly for severe psoriasis and keratinization disorders.
It works by regulating epidermal cell growth and differentiation, reducing excessive skin cell proliferation and inflammation.
Acitretin is particularly effective in pustular psoriasis, erythrodermic psoriasis, and extensive plaque psoriasis.
The drug helps normalize keratinization and decreases scaling, erythema, and plaque thickness.
Due to its teratogenic potential and systemic adverse effects, careful monitoring and strict pregnancy prevention are required during and after therapy.