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التصنيف: antihypertensive.ace
المادة الفعالة: enalapril

Enalapril is an angiotensin-converting enzyme (ACE) inhibitor prodrug converted to enalaprilat in the liver.
It inhibits ACE, reducing conversion of angiotensin I to angiotensin II, a potent vasoconstrictor.
This leads to vasodilation, decreased aldosterone secretion, and reduced sodium and water retention.
It lowers blood pressure and decreases preload and afterload, improving cardiac output in heart failure.
Indications include hypertension, heart failure, asymptomatic left ventricular dysfunction, and diabetic nephropathy.