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التصنيف: antihyperlipidemic
المادة الفعالة: evolocumab

evolocumab is a monoclonal antibody designed for the treatment of hyperlipidemia.
evolocumab is a fully human monoclonal antibody that inhibits proprotein convertase subtilisin/kexin type 9 (pcsk9).
pcsk9 is a protein that targets ldl receptors for degradation of the LDLR in endosomes/lysosomes, resulting in increased circulating LDLc.