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التصنيف: analgesic .nsaid.acetic acid derivatives
المادة الفعالة: diclofenac potassium

Diclofenac potassium is a non-steroidal anti-inflammatory drug (NSAID) with potent analgesic, anti-inflammatory, and antipyretic properties.

Mechanism of Action: It acts by competitively inhibiting the cyclooxygenase (COX-1 and COX-2) enzymes, which are responsible for the biosynthesis of pro-inflammatory prostaglandins from arachidonic acid.

Onset & Absorption: The potassium salt formulation provides rapid dissolution and absorption in the gastrointestinal tract, leading to a quick onset of peak plasma concentrations and fast pain relief.

Pharmacodynamics: By lowering peripheral prostaglandin levels, it reduces the sensitization of sensory nerve endings to painful stimuli and suppresses hypothalamic thermal regulation to lower fever.

Indications: Clinically indicated for the short-term management of acute mild-to-moderate pain, acute musculoskeletal injuries, primary dysmenorrhea, migraine attacks, and postoperative inflammation.